Health Service Focus

27.11.19

Why CBD, Why Now? - Mile High Labs

Source: NHE Nov/Dec

Dr Keith Aquachief medical officer, Mile High Labs

Last year I became the Chief Medical Officer of Mile High Labs, the world’s largest processor of hemp-derived CBD. Based in Broomfield, Colorado, Mile High Labs is not a medicinal cannabis company, rather a large-scale CBD ingredient and product manufacturer that supplies high-quality, high-volume CBD orders of bulk CBD and private label services to the world’s leading consumer brands. The company is now also focusing on developing the UK and European markets, opening its European headquarters in Belfast, Northern Ireland earlier this year.

So why did I accept the invitation to join, and why do I think that CBD is worth investigating, from a medical and wellness point of view?

As a medical doctor and practicing physician, I am frequently asked by my patients if CBD, either as an isolate or distillate, or even in combination with THC, is safe to ingest. People are curious about what they have heard about CBD. As I began to research the answers, I realised that no defined doses have been established. Essential safety parameters, like maximum daily dose and drug interactions, need to be determined if someone is going to ingest CBD. Basic questions like are you taking CBD for wellness or trying to improve pain, sleep, or anxiety due to a specific medical condition, need to be ascertained. Essentially, a thorough history needs to be obtained.

What interests me as a clinician and scientist is how to best protect the public by helping to understand the risks and benefits of any product. Working with Mile High Labs will allow the appropriate research to expand the knowledge base relating to CBD. This way consumers can make informed choices based on their individual needs and health professionals can counsel patients to be able to self-administer a standard amount or to have a manufacturer infuse a quantity of CBD that has been proven to be safe and efficacious. It is our intent to understand CBD as a nutraceutical for general consumption as well as for multiple medical indications.

Cannabinoids, the active compounds found within the cannabis plant, refer to a heterogeneous group of molecules that demonstrate activity on the endocannabinoid system (ECS). Cannabidiol (CBD) is one of 142 phyto-cannabinoids that have been isolated from hemp (1). The chemistry and pharmacology of CBD has been extensively studied and it induces markedly different physiological and psychological effects compared to the most well-known marijuana compound delta9- tetrahydrocannabinol (THC).

Within the endocannabinoid system, there are at least two receptors, CB, existing primarily on central and peripheral neurons, and CB, existing mainly on immune cells. By reacting with these receptors, CBD influences cells in the ECS all over the body. Many people contend, without sufficient evidence, that CBD has a wide range of therapeutic effects, including neuroprotective, anti-inflammatory, analgesic, anti-oxidative and anxiolytic. Unfortunately, most of these claims have been unproven as there has been a paucity of randomised, placebo-controlled clinical trials proving intended endpoints.

Over the past several years, researchers have reviewed the chemistry and pharmacology of CBD. There has been a plethora of data generated from animal studies, pre-clinical investigations, as well as anecdotal case reports. The recent FDA approval of Epidiolex (CBD oral solution) for the treatment of seizures associated with two rare and severe forms of paediatric epilepsy, demonstrates that there is a true medical benefit to CBD.

The extensive scrutiny and scientific research that went into proving the effectiveness of CBD at preventing seizures now needs to be applied to other indications. These disease processes may also benefit from CBD’s possible other properties. Unfortunately, and partially due to a worldwide lack of consistent regulatory control, extensive and pervasive mislabelling of CBD products exists. Independent research into online sales of CBD products has demonstrated that 43% of those products are under-labelled while 26% are over-labelled for actual CBD content.

These are the early days in the new, but rapidly expanding CBD industry. Despite minimal marketing, advertising, and with a somewhat sceptical media, sales of different CBD products are escalating. The public appetite for CBD and the abundance of products which now contain it, are multiplying at an exponential rate. As physicians, I believe it’s now our role to ensure that consumers are protected, that evidence is gathered and presented, and that the benefits of this versatile molecule are made available to all consumers.

FOR MORE INFORMATION

Tw: @MileHighLabs

W: www.milehighlabs.com

Comments

There are no comments. Why not be the first?

Add your comment

 

national health executive tv

more videos >

latest healthcare news

Number of nurses increases by 8,570 in the past year

27/02/2020Number of nurses increases by 8,570 in the past year

The Government has announced nursing numbers in the NHS have gone up by 8,570 nurses over the past year, as they work towards their ambitious goa... more >
NHS Digital annual report shows increase in adult social care workforce

27/02/2020NHS Digital annual report shows increase in adult social care workforce

An additional 1,000 adult social services roles were filled in local authorities across England, according to the latest NHS Digital annual repor... more >
NICE recommends new treatment for follicular lymphoma

27/02/2020NICE recommends new treatment for follicular lymphoma

The National Institute for Health and Care Excellence (NICE) have published final draft guidance approving a new treatment option for patien... more >

editor's comment

25/09/2017A hotbed of innovation

This edition of NHE comes hot on the heels of this year’s NHS Expo which, once again, proved to be a huge success at Manchester Central. A number of announcements were made during the event, with the health secretary naming the second wave of NHS digital pioneers, or ‘fast followers’, which follow the initial global digital e... read more >

last word

Haseeb Ahmad: ‘We all have a role to play in getting innovations quicker’

Haseeb Ahmad: ‘We all have a role to play in getting innovations quicker’

Haseeb Ahmad, president of the Association of the British Pharmaceutical Industry (ABPI), sits down with National Health Executive as part of our Last Word Q&A series. Would you talk us th... more > more last word articles >

the scalpel's daily blog

Too much emphasis on leadership development… and not enough

24/02/2020Too much emphasis on leadership development… and not enough

Words by Dean Royles and Kevan Taylor, who continue their regular contribution to NHE’s blog content. Kevan and Dean work in organisations and systems providing strategic support, advice and development. Every time the NHS goes through one of its many, many structural reorganisations, there is a renewed emphasis on the importance of leadership development. This is a good thing. We know the importance and value of good leadership a... more >
read more blog posts from 'the scalpel' >

comment

NHS England dementia director prescribes rugby for mental health and dementia patients

23/09/2019NHS England dementia director prescribes rugby for mental health and dementia patients

Reason to celebrate as NHS says watching rugby can be good for your mental health and wellbeing. As the best rugby players in the world repr... more >
Peter Kyle MP: It’s time to say thank you this Public Service Day

21/06/2019Peter Kyle MP: It’s time to say thank you this Public Service Day

Taking time to say thank you is one of the hidden pillars of a society. Being on the receiving end of some “thanks” can make communit... more >
Nurses named as least-appreciated public sector workers

13/06/2019Nurses named as least-appreciated public sector workers

Nurses have been named as the most under-appreciated public sector professionals as new research reveals how shockingly under-vauled our NHS, edu... more >
Creating the Cardigan integrated care centre

10/06/2019Creating the Cardigan integrated care centre

Peter Skitt, county director and commissioner for Ceredigion Hywel Dda University Health Board, looks ahead to the new integrated care centre bei... more >
Helpforce to launch training programmes for NHS volunteers

10/06/2019Helpforce to launch training programmes for NHS volunteers

Kay Fawcett OBE, clinical advisor and education lead at Helpforce, and Lynn Twinn, talent development consultant, outline the new national traini... more >

interviews

Mike Farrar, Swim England - Last Word

07/12/2019Mike Farrar, Swim England - Last Word

Mike Farrar Chairperson of Swim England Would you talk us through your previous roles within the NHS? I’ve held a number of ... more >
Matt Hancock says GP recruitment is on the rise to support ‘bedrock of the NHS’

24/10/2019Matt Hancock says GP recruitment is on the rise to support ‘bedrock of the NHS’

Today, speaking at the Royal College of General Practitioners (RCGP) annual conference, Matt Hancock highlighted what he believes to be the three... more >
NHS dreams come true for Teesside domestic

17/09/2019NHS dreams come true for Teesside domestic

Over 20 years ago, a Teesside hospital cleaner put down her mop and took steps towards her midwifery dreams. Lisa Payne has been delivering ... more >
How can winter pressures be dealt with? Introduce a National Social Care Service, RCP president suggests

24/10/2018How can winter pressures be dealt with? Introduce a National Social Care Service, RCP president suggests

A dedicated national social care service could be a potential solution to surging demand burdening acute health providers over the winter months,... more >
RCP president on new Liverpool college building: ‘This will be a hub for clinicians in the north’

24/10/2018RCP president on new Liverpool college building: ‘This will be a hub for clinicians in the north’

The president of the Royal College of Physicians (RCP) has told NHE that the college’s new headquarters based in Liverpool will become a hu... more >