News

12.07.19

Finger-prick blood test could reduce antibiotic use in COPD patients

A simple finger-prick blood test could help prevent unnecessary prescribing of antibiotics for people with the lung condition chronic obstructive pulmonary disease (COPD), according to NIHR-funded research.

Researchers from Cardiff University, University of Oxford and King’s College London demonstrated that using a CRP finger-prick blood test resulted in 20% fewer people using antibiotics for COPD flare-ups.

Importantly, this reduction in antibiotic use did not show to have a negative effect on patients’ recovery over the first two weeks after their consultation at their GP surgery, or on their well-being or use of health care services over the following six months.

READ MORE: Record numbers take part in Greater Manchester clinical research

The PACE study has been funded by the NIHR’s Health Technology Assessment (HTA) Programme and supported by the NIHR Clinical Research Network (CRN).

A paper has been published in the New England Journal of Medicine (NEJM).

Safely reducing the use of antibiotics in this way may help in the battle against antibiotic resistance.

More than a million people in the UK have COPD, which is a lung condition associated with smoking and other environmental pollutants. People living with the condition often experience exacerbations, or flare-ups, and when this happens, three out of four are prescribed antibiotics.

However, two-thirds of these flare-ups are not caused by bacterial infections and antibiotics often do not benefit patients.

READ MORE: New NIHR Academy launched to future-proof UK research workforce

Professor Nick Francis, from Cardiff University’s School of Medicine, said: “Governments, commissioners, clinicians, and patients living with COPD around the world are urgently seeking tools to help them know when it is safe to withhold antibiotics and focus on treating flare-ups with other treatments.

“This is a patient population that are often considered to be at high risk from not receiving antibiotics, but we were able to achieve a reduction in antibiotic use that is about twice the magnitude of that achieved by most other antimicrobial stewardship interventions, and demonstrate that this approach was safe.”

More information on the PACE study is available on the NIHR Journals Library website.

Comments

There are no comments. Why not be the first?

Add your comment

 

national health executive tv

more videos >

latest news

View all News

comment

NHS England dementia director prescribes rugby for mental health and dementia patients

23/09/2019NHS England dementia director prescribes rugby for mental health and dementia patients

Reason to celebrate as NHS says watching rugby can be good for your mental ... more >
Peter Kyle MP: It’s time to say thank you this Public Service Day

21/06/2019Peter Kyle MP: It’s time to say thank you this Public Service Day

Taking time to say thank you is one of the hidden pillars of a society. Bei... more >

editor's comment

25/09/2017A hotbed of innovation

This edition of NHE comes hot on the heels of this year’s NHS Expo which, once again, proved to be a huge success at Manchester Central. A number of announcements were made during the event, with the health secretary naming the second wave of NHS digital pioneers, or ‘fast followers’, which follow the initial global digital exemplars who were revealed at the same show 12 months earlier.  Jeremy Hunt also stated that by the end of 2018 – the 70th birthday... read more >

last word

Haseeb Ahmad: ‘We all have a role to play in getting innovations quicker’

Haseeb Ahmad: ‘We all have a role to play in getting innovations quicker’

Haseeb Ahmad, president of the Association of the British Pharmaceutical Industry (ABPI), sits down with National Health Executive as part of our Last Word Q&A series. Would you talk us throu more > more last word articles >

interviews

NHS dreams come true for Teesside domestic

17/09/2019NHS dreams come true for Teesside domestic

Over 20 years ago, a Teesside hospital cleaner put down her mop and took st... more >

the scalpel's daily blog

Providers are delivering – and here’s how

09/10/2019Providers are delivering – and here’s how

It has been a challenging few years for healthcare providers, yet they have continued to deliver high quality care despite the conditions. Adam Brimelow, director of comm... more >
read more blog posts from 'the scalpel' >

healthcare events

events calendar

back

October 2019

forward
mon tue wed thu fri sat sun
30 1 2 3 4 5 6
7 8 9 10 11 12 13
14 15 16 17 18 19 20
21 22 23 24 25 26 27
28 29 30 31 1 2 3
4 5 6 7 8 9 10

featured articles

View all News